About GTPase IMAP family member 8
GTPase IMAP family member 8 (GIMAP8) is a protein
from Homo sapiens identified by UniProt accession
Q8ND71, 665 residues long.
MolForge cross-references it against 0 known binders and
67 disease associations.
Target properties
| Protein name | GTPase IMAP family member 8 |
|---|
| UniProt accession | Q8ND71 |
|---|
| Gene | GIMAP8 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 665 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8ND71-F1 | alphafold | PREDICTED | 81.75 | — |
Amino-acid sequence (665 residues)
MSEQSCQMSE LRLLLLGKCR SGKSATGNAI LGKHVFKSKF SDQTVIKMCQ RESWVLRERK VVVIDTPDLF SSIACAEDKQ RNIQHCLELS APSLHALLLV IAIGHFTRED EETAKGIQQV FGAEARRHII IVFTRKDDLG DDLLQDFIEK NKPLKQLVQD YEGRYCIFNN KTNSKDEQIT QVLELLRKVE SLVNTNGGPY HVNFKTEGSR FQDCVNEAAS QEGDKPQGPR ERQLQSTGPE QNPGTSELTV LLVGKRGAGK SAAGNSILGR QAFQTGFSEQ SVTQSFLSES RSWRKKKVSI IDAPDISSLK NIDSEVRKHI CTGPHAFLLV TPLGFYTKND EAVLSTIQNN FGEKFFEYMI ILLTRKEDLG DQDLDTFLRN SNKALYGLIQ KCKNRYSAFN YRATGEEEQR QADELLEKIE SMVHQNGNKH CVFREKETLN IVLVGRSGTG KSATGNSILG SLVFTSRLRA QPVTKTSQSG RRTWDGQEVV VVDTPSFNQM LDVEKDPSRL EEEVKRCLSC CEKGDTFFVL VFQLGRFTEE DKTAVAKLEA IFGADFTKYA IMLFTRKEDL GAGNLEDFMK NSDNKALRRI FKKCGRRVCA FNNKETGQAQ ETQVKALLTK VNDLRKESGW SGYPHTQENV SKLIKNVQEM SQAEKLLKNL IGILQ
Explore GTPase IMAP family member 8 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets