About Cyclin-Y
Cyclin-Y (CCNY) is a protein
from Homo sapiens identified by UniProt accession
Q8ND76, 341 residues long.
MolForge cross-references it against 0 known binders and
56 disease associations.
Target properties
| Protein name | Cyclin-Y |
|---|
| UniProt accession | Q8ND76 |
|---|
| Gene | CCNY |
|---|
| Organism | Homo sapiens |
|---|
| Length | 341 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (56)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.36
- psoriasis · score 0.27
- Crohn's disease · score 0.13
- hair color · score 0.13
- non-small cell lung carcinoma · score 0.10
- age at first facial hair · score 0.08
- hepatocellular carcinoma · score 0.08
- neoplasm · score 0.07
- ulcerative colitis · score 0.06
- waist-hip ratio · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8ND76-F1 | alphafold | PREDICTED | 78.39 | — |
Amino-acid sequence (341 residues)
MGNTTSCCVS SSPKLRRNAH SRLESYRPDT DLSREDTGCN LQHISDRENI DDLNMEFNPS DHPRASTIFL SKSQTDVREK RKSLFINHHP PGQIARKYSS CSTIFLDDST VSQPNLKYTI KCVALAIYYH IKNRDPDGRM LLDIFDENLH PLSKSEVPPD YDKHNPEQKQ IYRFVRTLFS AAQLTAECAI VTLVYLERLL TYAEIDICPA NWKRIVLGAI LLASKVWDDQ AVWNVDYCQI LKDITVEDMN ELERQFLELL QFNINVPSSV YAKYYFDLRS LAEANNLSFP LEPLSRERAH KLEAISRLCE DKYKDLRRSA RKRSASADNL TLPRWSPAII S
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