SLAIN motif-containing protein 1 (SLAIN1)

About SLAIN motif-containing protein 1

SLAIN motif-containing protein 1 (SLAIN1) is a protein from Homo sapiens identified by UniProt accession Q8ND83, 568 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein name	SLAIN motif-containing protein 1
UniProt accession	Q8ND83
Gene	SLAIN1
Organism	Homo sapiens
Length	568 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (38)

Diseases linked to this target (Open Targets).

body mass index · score 0.42
lymphocyte count · score 0.42
hair color · score 0.39
hair colour measurement · score 0.32
leukocyte count · score 0.28
neurodegenerative disease · score 0.25
skin pigmentation · score 0.25
myeloid white cell count · score 0.24
serum gamma-glutamyl transferase measurement · score 0.21
monocyte count · score 0.20

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8ND83-F1	alphafold	PREDICTED	53.83	—

Amino-acid sequence (568 residues)

MMAEQVKCAS AGVSSGAGSG PVVNAELEVK KLQELVRKLE KQNEQLRSRA ASAAAAPHLL LLPPPPPAAP PPAGLQPLGP RSPPAATATA AASGGLGPAF PGTFCLPSPA PSLLCSLAQP PEAPFVYFKP AAGFFGAGGG GPEPGGAGTP PGAAAAPPSP PPTLLDEVEL LDLESVAAWR DEDDYTWLYI GSSKTFTSSE KSLTPLQWCR HVLDNPTPEM EAARRSLCFR LEQGYTSRGS PLSPQSSIDS ELSTSELEDD SISMGYKLQD LTDVQIMARL QEESLRQDYA STSASVSRHS SSVSLSSGKK GTCSDQEYDQ YSLEDEEEFD HLPPPQPRLP RCSPFQRGIP HSQTFSSIRE CRRSPSSQYF PSNNYQQQQY YSPQAQTPDQ QPNRTNGDKL RRSMPNLARM PSTTAISSNI SSPVTVRNSQ SFDSSLHGAG NGISRIQSCI PSPGQLQHRV HSVGHFPVSI RQPLKATAYV SPTVQGSSNM PLSNGLQLYS NTGIPTPNKA AASGIMGRSA LPRPSLAING SNLPRSKIAQ PVRSFLQPPK PLSSLSTLRD GNWRDGCY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards