About LRRN4 C-terminal-like protein
LRRN4 C-terminal-like protein (LRRN4CL) is a protein
from Homo sapiens identified by UniProt accession
Q8ND94, 238 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | LRRN4 C-terminal-like protein |
| UniProt accession | Q8ND94 |
| Gene | LRRN4CL |
| Organism | Homo sapiens |
| Length | 238 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- melanoma · score 0.06
- colorectal cancer · score 0.03
- cancer · score 0.03
- reticulocyte measurement · score 0.02
- body fat percentage · score 0.02
- glioblastoma multiforme · score 0.02
- neoplasm · score 0.02
- Uveal melanoma · score 0.01
- endometrial carcinoma · score 0.01
- invasive breast ductal carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q8ND94-F1 | alphafold | PREDICTED | 81.53 | — |
Amino-acid sequence (238 residues)
MLGSPCLLWL LAVTFLVPRA QPLAPQDFEE EEADETETAW PPLPAVPCDY DHCRHLQVPC KELQRVGPAA CLCPGLSSPA QPPDPPRMGE VRIAAEEGRA VVHWCAPFSP VLHYWLLLWD GSEAAQKGPP LNATVRRAEL KGLKPGGIYV VCVVAANEAG ASRVPQAGGE GLEGADIPAF GPCSRLAVPP NPRTLVHAAV GVGTALALLS CAALVWHFCL RDRWGCPRRA AARAAGAL
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