Zinc finger protein 439 (ZNF439)

About Zinc finger protein 439

Zinc finger protein 439 (ZNF439) is a protein from Homo sapiens identified by UniProt accession Q8NDP4, 499 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.

Target properties

Protein name	Zinc finger protein 439
UniProt accession	Q8NDP4
Gene	ZNF439
Organism	Homo sapiens
Length	499 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (18)

Diseases linked to this target (Open Targets).

calcium measurement · score 0.29
vitamin D measurement · score 0.22
eosinophil count · score 0.15
pancreatic adenocarcinoma · score 0.14
leukocyte count · score 0.08
blood phosphate measurement · score 0.06
IGF-1 measurement · score 0.05
neutrophil count · score 0.05
Down syndrome · score 0.04
colorectal adenocarcinoma · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NDP4-F1	alphafold	PREDICTED	69.27	—

Amino-acid sequence (499 residues)

MLSLSPILLY TCEMFQDPVA FKDVAVNFTQ EEWALLDISQ KNLYREVMLE TFWNLTSIGK KWKDQNIEYE YQNPRRNFRS VTEEKVNEIK EDSHCGETFT PVPDDRLNFQ KKKASPEVKS CDSFVCEVGL GNSSSNMNIR GDTGHKACEC QEYGPKPWKS QQPKKAFRYH PSLRTQERDH TGKKPYACKE CGKNIIYHSS IQRHMVVHSG DGPYKCKFCG KAFHCLSLYL IHERTHTGEK PYECKQCGKS FSYSATHRIH ERTHIGEKPY ECQECGKAFH SPRSCHRHER SHMGEKAYQC KECGKAFMCP RYVRRHERTH SRKKLYECKQ CGKALSSLTS FQTHIRMHSG ERPYECKTCG KGFYSAKSFQ RHEKTHSGEK PYKCKQCGKA FTRSGSFRYH ERTHTGEKPY ECKQCGKAFR SAPNLQLHGR THTGEKPYQC KECGKAFRSA SQLRIHRRIH TGEKPYECKK CGKAFRYVQN FRFHERTQTH KNALWRKTL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards