About Zinc finger protein 248
Zinc finger protein 248 (ZNF248) is a protein
from Homo sapiens identified by UniProt accession
Q8NDW4, 579 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | Zinc finger protein 248 |
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| UniProt accession | Q8NDW4 |
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| Gene | ZNF248 |
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| Organism | Homo sapiens |
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| Length | 579 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
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Disease associations (13)
Diseases linked to this target (Open Targets).
- IGF-1 measurement · score 0.12
- appendicular lean mass · score 0.07
- response to antidepressant · score 0.06
- Ataxia-telangiectasia · score 0.05
- response to selective serotonin reuptake inhibitor · score 0.05
- triglyceride measurement · score 0.05
- glioblastoma multiforme · score 0.01
- psoriasis · score 0.01
- Alzheimer disease · score 0.01
- genetic disorder · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NDW4-F1 | alphafold | PREDICTED | 55.71 | — |
Amino-acid sequence (579 residues)
MNKSQEQVSF KDVCVDFTQE EWYLLDPAQK ILYRDVILEN YSNLVSVGYC ITKPEVIFKI EQGEEPWILE KGFPSQCHPE RKWKVDDVLE SSQENEDDHF WELLFHNNKT VSVENGDRGS KTFNLGTDPV SLRNYPYKIC DSCEMNLKNI SGLIISKKNC SRKKPDEFNV CEKLLLDIRH EKIPIGEKSY KYDQKRNAIN YHQDLSQPSF GQSFEYSKNG QGFHDEAAFF TNKRSQIGET VCKYNECGRT FIESLKLNIS QRPHLEMEPY GCSICGKSFC MNLRFGHQRA LTKDNPYEYN EYGEIFCDNS AFIIHQGAYT RKILREYKVS DKTWEKSALL KHQIVHMGGK SYDYNENGSN FSKKSHLTQL RRAHTGEKTF ECGECGKTFW EKSNLTQHQR THTGEKPYEC TECGKAFCQK PHLTNHQRTH TGEKPYECKQ CGKTFCVKSN LTEHQRTHTG EKPYECNACG KSFCHRSALT VHQRTHTGEK PFICNECGKS FCVKSNLIVH QRTHTGEKPY KCNECGKTFC EKSALTKHQR THTGEKPYEC NACGKTFSQR SVLTKHQRIH TRVKALSTS
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