Protein FAM13C (FAM13C)

About Protein FAM13C

Protein FAM13C (FAM13C) is a protein from Homo sapiens identified by UniProt accession Q8NE31, 585 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.

Target properties

Protein name	Protein FAM13C
UniProt accession	Q8NE31
Gene	FAM13C
Organism	Homo sapiens
Length	585 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (39)

Diseases linked to this target (Open Targets).

Familial prostate cancer · score 0.11
prostate carcinoma · score 0.11
prostate cancer · score 0.11
metabolite measurement · score 0.08
hemoglobin measurement · score 0.08
DNA methylation · score 0.05
triglyceride measurement · score 0.05
urate measurement · score 0.05
body height · score 0.05
vital capacity · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NE31-F1	alphafold	PREDICTED	60.51	—

Amino-acid sequence (585 residues)

MFSCFCFSLQ DNSFSSTTVT ECDEDPVSLH EDQTDCSSLR DENNKENYPD AGALVEEHAP PSWEPQQQNV EATVLVDSVL RPSMGNFKSR KPKSIFKAES GRSHGESQET EHVVSSQSEC QVRAGTPAHE SPQNNAFKCQ ETVRLQPRID QRTAISPKDA FETRQDLNEE EAAQVHGVKD PAPASTQSVL ADGTDSADPS PVHKDGQNEA DSAPEDLHSV GTSRLLYHIT DGDNPLLSPR CSIFSQSQRF NLDPESAPSP PSTQQFMMPR SSSRCSCGDG KEPQTITQLT KHIQSLKRKI RKFEEKFEQE KKYRPSHGDK TSNPEVLKWM NDLAKGRKQL KELKLKLSEE QGSAPKGPPR NLLCEQPTVP RENGKPEAAG PEPSSSGEET PDAALTCLKE RREQLPPQED SKVTKQDKNL IKPLYDRYRI IKQILSTPSL IPTIQEEEDS DEDRPQGSQQ PSLADPASHL PVGDHLTYSN ETEPVRALLP DEKKEVKPPA LSMSNLHEAT MPVLLDHLRE TRADKKRLRK ALREFEEQFF KQTGRSPQKE DRIPMADEYY EYKHIKAKLR LLEVLISKQD VAKTI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards