About F-box and leucine-rich repeat protein 13
F-box and leucine-rich repeat protein 13 (FBXL13) is a protein
from Homo sapiens identified by UniProt accession
Q8NEE6, 735 residues long.
MolForge cross-references it against 0 known binders and
28 disease associations.
Target properties
| Protein name | F-box and leucine-rich repeat protein 13 |
|---|
| UniProt accession | Q8NEE6 |
|---|
| Gene | FBXL13 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 735 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (28)
Diseases linked to this target (Open Targets).
- chronotype measurement · score 0.37
- clear cell renal carcinoma · score 0.18
- response to cold pressor test · score 0.15
- mean arterial pressure · score 0.15
- cortical thickness · score 0.14
- brain measurement · score 0.12
- cortical surface area measurement · score 0.11
- diverticulitis · score 0.10
- type 2 diabetes mellitus · score 0.10
- diverticular disease · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NEE6-F1 | alphafold | PREDICTED | 88.55 | — |
Amino-acid sequence (735 residues)
MTPELMIKAC SFYTGHLVKT HFCTWRDIAR TNENVVLAEK MNRAVTCYNF RLQKSVFHHW HSYMEDQKEK LKNILLRIQQ IIYCHKLTII LTKWRNTARH KSKKKEDELI LKHELQLKKW KNRLILKRAA AEESNFPERS SSEVFLVDET LKCDISLLPE RAILQIFFYL SLKDVIICGQ VNHAWMLMTQ LNSLWNAIDF SSVKNVIPDK YIVSTLQRWR LNVLRLNFRG CLLRPKTFRS VSHCRNLQEL NVSDCPTFTD ESMRHISEGC PGVLCLNLSN TTITNRTMRL LPRHFHNLQN LSLAYCRRFT DKGLQYLNLG NGCHKLIYLD LSGCTQISVQ GFRYIANSCT GIMHLTINDM PTLTDNCVKA LVEKCSRITS LVFTGAPHIS DCTFRALSAC KLRKIRFEGN KRVTDASFKF IDKNYPNLSH IYMADCKGIT DSSLRSLSPL KQLTVLNLAN CVRIGDMGLK QFLDGPASMR IRELNLSNCV RLSDASVMKL SERCPNLNYL SLRNCEHLTA QGIGYIVNIF SLVSIDLSGT DISNEGLNVL SRHKKLKELS VSECYRITDD GIQAFCKSSL ILEHLDVSYC SQLSDMIIKA LAIYCINLTS LSIAGCPKIT DSAMEMLSAK CHYLHILDIS GCVLLTDQIL EDLQIGCKQL RILKMQYCTN ISKKAAQRMS SKVQQQEYNT NDPPRWFGYD REGNPVTELD NITSSKGALE LTVKKSTYSS EDQAA
Explore F-box and leucine-rich repeat protein 13 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets