About Uncharacterized protein C7orf57
Uncharacterized protein C7orf57 (C7orf57) is a protein
from Homo sapiens identified by UniProt accession
Q8NEG2, 295 residues long.
MolForge cross-references it against 0 known binders and
22 disease associations.
Target properties
| Protein name | Uncharacterized protein C7orf57 |
|---|
| UniProt accession | Q8NEG2 |
|---|
| Gene | C7orf57 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 295 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (22)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.37
- leukocyte count · score 0.31
- dislocation · score 0.30
- sprain · score 0.30
- muscle strain · score 0.30
- myeloid white cell count · score 0.15
- metabolite measurement · score 0.07
- central nervous system cancer · score 0.04
- ependymoma · score 0.04
- sphingomyelin measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NEG2-F1 | alphafold | PREDICTED | 63.51 | — |
Amino-acid sequence (295 residues)
MRNTSKELQG ATHRYAPCDW YYHVPVKRSE KAVDAPPASQ IPGLSNLGDS HSENLPGTRR YWIKETDSEY VKLAKQGGRP DLLKHFAPGT RKGSPVAYSL PDWYIHHSKP PTASQQEVRA VSMPDYMVHE EFNPDQANGS YASRRGPFDF DMKTVWQREA EELEKEKKKL RLPAIDSKYL SKAGTPLGPK NPAGSRLSFP PVPGQKNSSP TNFSKLISNG YKDEWLQQQQ RADSDKRTPK TSRASVLSQS PRDLEGPQDA ARLQDAEASE GPEDTPESSQ SPEESVSAST PAELK
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