About Kelch domain-containing protein 9
Kelch domain-containing protein 9 (KLHDC9) is a protein
from Homo sapiens identified by UniProt accession
Q8NEP7, 349 residues long.
MolForge cross-references it against 0 known binders and
5 disease associations.
Target properties
| Protein name | Kelch domain-containing protein 9 |
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| UniProt accession | Q8NEP7 |
|---|
| Gene | KLHDC9 |
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| Organism | Homo sapiens |
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| Length | 349 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (5)
Diseases linked to this target (Open Targets).
- serum gamma-glutamyl transferase measurement · score 0.03
- lung adenocarcinoma · score 0.01
- Tetralogy of Fallot · score 0.01
- IGA glomerulonephritis · score 0.00
- ulcerative colitis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NEP7-F1 | alphafold | PREDICTED | 92.91 | — |
Amino-acid sequence (349 residues)
MAVAVPPGRA AGSGWAWRPV ARDALLARAF HSCTELRGRF YLVGGLLAGG AREPSSDTVV FDPARGQAVR LGARGSPPRS HHDAAPVDGR WLCVVGGWDG SRRLATVTAL DTERGVWEAW TGTPGDCPPA GLSSHTCTRI SDRELQVAGR EGGIHTQRRY GSIYTLRLDP SARTYCYKQE GCHTASRSGH CAALLQTPGP HPGHQLLLFG GCNLAEPEVA GHWSHGKIKE EPPVAPHLME QLARLVSSGQ GSQKGPHGLR HHSCSVVGPF AVLFGGETLT RARDTICNDL YIYDTRTSPP LWFHFPCADR GMKRMGHRTC LWNDQLYLVG GFGEDGRTAS PQVCILDFI
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