About Zinc finger protein 555
Zinc finger protein 555 (ZNF555) is a protein
from Homo sapiens identified by UniProt accession
Q8NEP9, 628 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Zinc finger protein 555 |
|---|
| UniProt accession | Q8NEP9 |
|---|
| Gene | ZNF555 |
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| Organism | Homo sapiens |
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| Length | 628 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (12)
Diseases linked to this target (Open Targets).
- pancreatic adenocarcinoma · score 0.14
- Facioscapulohumeral dystrophy · score 0.07
- facioscapulohumeral muscular dystrophy · score 0.07
- sex hormone-binding globulin measurement · score 0.06
- testosterone measurement · score 0.05
- platelet count · score 0.04
- low density lipoprotein cholesterol measurement · score 0.04
- total cholesterol measurement · score 0.04
- platelet crit · score 0.02
- neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NEP9-F1 | alphafold | PREDICTED | 68.40 | — |
Amino-acid sequence (628 residues)
MDSVVFEDVA VDFTLEEWAL LDSAQRDLYR DVMLETFQNL ASVDDETQFK ASGSVSQQDI YGEKIPKESK IATFTRNVSW ASVLGKIWDS LSIEDQTTNQ GRNLSRNHGL ERLCESNDQC GEALSQIPHL NLYKKIPPGV KQYEYNTYGK VFMHRRTSLK SPITVHTGHK PYQCQECGQA YSCRSHLRMH VRTHNGERPY VCKLCGKTFP RTSSLNRHVR IHTAEKTYEC KQCGKAFIDF SSLTSHLRSH TGEKPYKCKE CGKAFSYSST FRRHTITHTG EKPYKCKECA EAFSYSSTFR RHMISHTGEK PHKCKECGEA FSYSSAFRRH MITHTGEKPY ECKQCGKTFI YLQSFRRHER IHTGEKPYEC KQCGKTFIYP QSFRRHERTH GGEKPYECNQ CGKAFSHPSS FRGHMRVHTG EKPYECKQCG KTFNWPISLR KHMRTHTREK PYECKQCGKA FSLSACFREH VRMHPEDKSY ECKLCGKAFY CHISLQKHMR RHTAEKLYKC KQCGKAFSWP ELLQQHVRTH TVEKPYECKE CGKVFKWPSS LPIHMRLHTG EKPYQCKHCG KAFNCSSSLR RHVRIHTTEK QYKCNVGHPP ANEFMCSASE KSHQERDLIK VVNMVLPL
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