Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (LFNG)

About Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe

Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (LFNG) is a protein from Homo sapiens identified by UniProt accession Q8NES3, 379 residues long. MolForge cross-references it against 0 known binders and 167 disease associations.

Target properties

Protein name	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
UniProt accession	Q8NES3
Gene	LFNG
Organism	Homo sapiens
Length	379 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NES3-F1	alphafold	PREDICTED	82.21	—

Amino-acid sequence (379 residues)

MLKRCGRRLL LALAGALLAC LLVLTADPPP PPLPAERGRR ALRSLAGPAG AAPAPGLGAA AAAPGALVRD VHSLSEYFSL LTRARRDAGP PPGAAPRPAD GHPRPLAEPL APRDVFIAVK TTKKFHRARL DLLLETWISR HKEMTFIFTD GEDEALARHT GNVVITNCSA AHSRQALSCK MAVEYDRFIE SGRKWFCHVD DDNYVNLRAL LRLLASYPHT RDVYVGKPSL DRPIQAMERV SENKVRPVHF WFATGGAGFC ISRGLALKMS PWASGGHFMN TAERIRLPDD CTIGYIVEAL LGVPLIRSGL FHSHLENLQQ VPTSELHEQV TLSYGMFENK RNAVHVKGPF SVEADPSRFR SIHCHLYPDT PWCPRTAIF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards