Beta-defensin 124 (DEFB124)

About Beta-defensin 124

Beta-defensin 124 (DEFB124) is a protein from Homo sapiens identified by UniProt accession Q8NES8, 71 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

Target properties

Protein name	Beta-defensin 124
UniProt accession	Q8NES8
Gene	DEFB124
Organism	Homo sapiens
Length	71 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NES8-F1	alphafold	PREDICTED	78.19	—

Amino-acid sequence (71 residues)

MTQLLLFLVA LLVLGHVPSG RSEFKRCWKG QGACQTYCTR QETYMHLCPD ASLCCLSYAL KPPPVPKHEY E

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards