Beta-defensin 108B (DEFB108B)

About Beta-defensin 108B

Beta-defensin 108B (DEFB108B) is a protein from Homo sapiens identified by UniProt accession Q8NET1, 73 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Beta-defensin 108B
UniProt accession	Q8NET1
Gene	DEFB108B
Organism	Homo sapiens
Length	73 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

calcium measurement · score 0.21
platelet count · score 0.14
Autosomal dominant striatal neurodegeneration · score 0.04
adolescent idiopathic scoliosis · score 0.03
chronic obstructive pulmonary disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NET1-F1	alphafold	PREDICTED	69.35	—

Amino-acid sequence (73 residues)

MRIAVLLFAI FFFMSQVLPA RGKFKEICER PNGSCRDFCL ETEIHVGRCL NSQPCCLPLG HQPRIESTTP KKD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards