Casein kinase II subunit alpha 3 (CSNK2A3)

About Casein kinase II subunit alpha 3

Casein kinase II subunit alpha 3 (CSNK2A3) is a protein from Homo sapiens identified by UniProt accession Q8NEV1, 391 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Casein kinase II subunit alpha 3
UniProt accession	Q8NEV1
Gene	CSNK2A3
Organism	Homo sapiens
Length	391 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

Okur-Chung neurodevelopmental syndrome · score 0.27
skin pigmentation measurement · score 0.18
urate measurement · score 0.16
bone density · score 0.16
alcohol drinking · score 0.15
systolic blood pressure · score 0.15
cerebrospinal fluid biomarker measurement · score 0.14
dimethylamine measurement · score 0.13
diastolic blood pressure · score 0.12
blood phosphate measurement · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NEV1-F1	alphafold	PREDICTED	88.90	—

Amino-acid sequence (391 residues)

MSGPVPSRAR VYTDVNTHRP REYWDYESHV VEWGNQDDYQ LVRKLGRGKY SEVFEAINIT NNEKVVVKIL KPVKKKKIKR EIKILENLRG GPNIITLADI VKDPVSRTPA LVFEHVNNTD FKQLYQTLTD YDIRFYMYEI LKALDYCHSM GIMHRDVKPH NVMIDHEHRK LRLIDWGLAE FYHPGQEYNV RVASRYFKGP ELLVDYQMYD YSLDMWRLGC MLASMIFRKE PFFHGRDNYD QLVRIAKFLG TEDLYGYIDK YNIELDPRFN DILGRHSRKR WERFVHSENQ HLVSPEALDF LDKLLRYDHQ SRLTAREAME HPYFYTVVKD QARMGSSSMP GGSTPVSSAN VMSGISSVPT PSPLGPLAGS PVIAAANPLG MPVPAATGAQ Q

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards