About Zinc transporter 7
Zinc transporter 7 (SLC30A7) is a protein
from Homo sapiens identified by UniProt accession
Q8NEW0, 376 residues long.
MolForge cross-references it against 0 known binders and
91 disease associations.
Target properties
| Protein name | Zinc transporter 7 |
|---|
| UniProt accession | Q8NEW0 |
|---|
| Gene | SLC30A7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 376 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (91)
Diseases linked to this target (Open Targets).
- Ziegler-Huang syndrome · score 0.51
- Joubert syndrome 1 · score 0.33
- Decreased testicular size · score 0.27
- Testicular atrophy · score 0.27
- lymphocyte percentage of leukocytes · score 0.23
- multiple sclerosis · score 0.22
- lymphocyte count · score 0.17
- reticulocyte count · score 0.14
- reticulocyte measurement · score 0.11
- Fuchs endothelial corneal dystrophy · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NEW0-F1 | alphafold | PREDICTED | 75.62 | — |
Amino-acid sequence (376 residues)
MLPLSIKDDE YKPPKFNLFG KISGWFRSIL SDKTSRNLFF FLCLNLSFAF VELLYGIWSN CLGLISDSFH MFFDSTAILA GLAASVISKW RDNDAFSYGY VRAEVLAGFV NGLFLIFTAF FIFSEGVERA LAPPDVHHER LLLVSILGFV VNLIGIFVFK HGGHGHSHGS GHGHSHSLFN GALDQAHGHV DHCHSHEVKH GAAHSHDHAH GHGHFHSHDG PSLKETTGPS RQILQGVFLH ILADTLGSIG VIASAIMMQN FGLMIADPIC SILIAILIVV SVIPLLRESV GILMQRTPPL LENSLPQCYQ RVQQLQGVYS LQEQHFWTLC SDVYVGTLKL IVAPDADARW ILSQTHNIFT QAGVRQLYVQ IDFAAM
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