About Protein WFDC11
Protein WFDC11 (WFDC11) is a protein
from Homo sapiens identified by UniProt accession
Q8NEX6, 87 residues long.
MolForge cross-references it against 0 known binders and
33 disease associations.
Target properties
| Protein name | Protein WFDC11 |
|---|
| UniProt accession | Q8NEX6 |
|---|
| Gene | WFDC11 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 87 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (33)
Diseases linked to this target (Open Targets).
- depressive symptom measurement · score 0.12
- retinitis pigmentosa · score 0.11
- age-related macular degeneration · score 0.09
- X-linked retinal dysplasia · score 0.08
- Progressive cone dystrophy · score 0.07
- Familial exudative vitreoretinopathy · score 0.07
- severe early-childhood-onset retinal dystrophy · score 0.06
- choroidal dystrophy, central areolar, 1 · score 0.06
- age related macular degeneration 11 · score 0.06
- age related macular degeneration 7 · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NEX6-F1 | alphafold | PREDICTED | 78.21 | — |
Amino-acid sequence (87 residues)
MVSLMKLWIP MLMTFFCTVL LSVLGEMRKK RYDRKELLLE ECWGKPNVKE CTNKCSKAFR CKDKNYTCCW TYCGNICWIN VETSGDY
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