About Short-chain dehydrogenase/reductase family 9C member 7
Short-chain dehydrogenase/reductase family 9C member 7 (SDR9C7) is a protein
from Homo sapiens identified by UniProt accession
Q8NEX9, 313 residues long.
MolForge cross-references it against 0 known binders and
50 disease associations.
Target properties
| Protein name | Short-chain dehydrogenase/reductase family 9C member 7 |
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| UniProt accession | Q8NEX9 |
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| Gene | SDR9C7 |
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| Organism | Homo sapiens |
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| Length | 313 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (50)
Diseases linked to this target (Open Targets).
- Ichthyosis-hypotrichosis syndrome · score 0.66
- inherited ichthyosis · score 0.44
- lamellar ichthyosis · score 0.44
- congenital non-bullous ichthyosiform erythroderma · score 0.37
- migraine disorder · score 0.20
- respiratory system disease · score 0.19
- genetic disorder · score 0.19
- depressive symptom measurement · score 0.11
- breast adenocarcinoma · score 0.11
- eosinophil percentage of leukocytes · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NEX9-F1 | alphafold | PREDICTED | 93.49 | — |
Amino-acid sequence (313 residues)
MAALTDLSFM YRWFKNCNLV GNLSEKYVFI TGCDSGFGNL LAKQLVDRGM QVLAACFTEE GSQKLQRDTS YRLQTTLLDV TKSESIKAAA QWVRDKVGEQ GLWALVNNAG VGLPSGPNEW LTKDDFVKVI NVNLVGLIEV TLHMLPMVKR ARGRVVNMSS SGGRVAVIGG GYCVSKFGVE AFSDSIRREL YYFGVKVCII EPGNYRTAIL GKENLESRMR KLWERLPQET RDSYGEDYFR IYTDKLKNIM QVAEPRVRDV INSMEHAIVS RSPRIRYNPG LDAKLLYIPL AKLPTPVTDF ILSRYLPRPA DSV
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