Spermatogenesis-associated protein 4 (SPATA4)

About Spermatogenesis-associated protein 4

Spermatogenesis-associated protein 4 (SPATA4) is a protein from Homo sapiens identified by UniProt accession Q8NEY3, 305 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.

Target properties

Protein name	Spermatogenesis-associated protein 4
UniProt accession	Q8NEY3
Gene	SPATA4
Organism	Homo sapiens
Length	305 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NEY3-F1	alphafold	PREDICTED	74.71	—

Amino-acid sequence (305 residues)

MAAAGQEKGY LTQTAAALDK SPSLSPQLAA PIRGRPKKCL VYPHAPKSSR LSRSVLRWLQ GLDLSFFPRN INRDFSNGFL IAEIFCIYYP WELELSSFEN GTSLKVKLDN WAQLEKFLAR KKFKLPKELI HGTIHCKAGV PEILIEEVYT LLTHREIKSI QDDFVNFTDY SYQMRLPLVS RSTVSKSIKD NIRLSELLSN PNMLTNELKA EFLILLHMLQ RKLGRKLNPE WFDVKPTVGE VTLNHLPAQA SGRRYNLKVK RGRVVPVLPN IGSGGSSHRE IHVKQAGQHS YYSAMKPIRN MDKKP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards