Vacuolar protein sorting-associated protein 37A (VPS37A)

About Vacuolar protein sorting-associated protein 37A

Vacuolar protein sorting-associated protein 37A (VPS37A) is a protein from Homo sapiens identified by UniProt accession Q8NEZ2, 397 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein name	Vacuolar protein sorting-associated protein 37A
UniProt accession	Q8NEZ2
Gene	VPS37A
Organism	Homo sapiens
Length	397 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NEZ2-F1	alphafold	PREDICTED	76.13	—

Amino-acid sequence (397 residues)

MSWLFPLTKS ASSSAAGSPG GLTSLQQQKQ RLIESLRNSH SSIAEIQKDV EYRLPFTINN LTININILLP PQFPQEKPVI SVYPPIRHHL MDKQGVYVTS PLVNNFTMHS DLGKIIQSLL DEFWKNPPVL APTSTAFPYL YSNPSGMSPY ASQGFPFLPP YPPQEANRSI TSLSVADTVS SSTTSHTTAK PAAPSFGVLS NLPLPIPTVD ASIPTSQNGF GYKMPDVPDA FPELSELSVS QLTDMNEQEE VLLEQFLTLP QLKQIITDKD DLVKSIEELA RKNLLLEPSL EAKRQTVLDK YELLTQMKST FEKKMQRQHE LSESCSASAL QARLKVAAHE AEEESDNIAE DFLEGKMEID DFLSSFMEKR TICHCRRAKE EKLQQAIAMH SQFHAPL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards