Serine protease 33 (PRSS33)

About Serine protease 33

Serine protease 33 (PRSS33) is a protein from Homo sapiens identified by UniProt accession Q8NF86, 280 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.

Target properties

Protein name	Serine protease 33
UniProt accession	Q8NF86
Gene	PRSS33
Organism	Homo sapiens
Length	280 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NF86-F1	alphafold	PREDICTED	85.68	—

Amino-acid sequence (280 residues)

MRGVSCLQVL LLLVLGAAGT QGRKSAACGQ PRMSSRIVGG RDGRDGEWPW QASIQHRGAH VCGGSLIAPQ WVLTAAHCFP RRALPAEYRV RLGALRLGST SPRTLSVPVR RVLLPPDYSE DGARGDLALL QLRRPVPLSA RVQPVCLPVP GARPPPGTPC RVTGWGSLRP GVPLPEWRPL QGVRVPLLDS RTCDGLYHVG ADVPQAERIV LPGSLCAGYP QGHKDACQGD SGGPLTCLQS GSWVLVGVVS WGKGCALPNR PGVYTSVATY SPWIQARVSF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards