Nucleoporin Nup43 (NUP43)

About Nucleoporin Nup43

Nucleoporin Nup43 (NUP43) is a protein from Homo sapiens identified by UniProt accession Q8NFH3, 380 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.

Target properties

Protein name	Nucleoporin Nup43
UniProt accession	Q8NFH3
Gene	NUP43
Organism	Homo sapiens
Length	380 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NFH3-F1	alphafold	PREDICTED	85.64	—

Amino-acid sequence (380 residues)

MEEIYAKFVS QKISKTRWRP LPPGSLQTAE TFATGSWDNE ENYISLWSIG DFGNLDSDGG FEGDHQLLCD IRHHGDVMDL QFFDQERIVA ASSTGCVTVF LHHPNNQTLS VNQQWTTAHY HTGPGSPSYS SAPCTGVVCN NPEIVTVGED GRINLFRADH KEAVRTIDNA DSSTLHAVTF LRTPEILTVN SIGQLKIWDF RQQGNEPSQI LSLTGDRVPL HCVDRHPNQQ HVVATGGQDG MLSIWDVRQG TMPVSLLKAH EAEMWEVHFH PSNPEHLFTC SEDGSLWHWD ASTDVPEKSS LFHQGGRSST FLSHSISNQA NVHQSVISSW LSTDPAKDRI EITSLLPSRS LSVNTLDVLG PCLVCGTDAE AIYVTRHLFS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards