About Probable G-protein coupled receptor 156
Probable G-protein coupled receptor 156 (GPR156) is a protein
from Homo sapiens identified by UniProt accession
Q8NFN8, 814 residues long.
MolForge cross-references it against 0 known binders and
22 disease associations.
Target properties
| Protein name | Probable G-protein coupled receptor 156 |
|---|
| UniProt accession | Q8NFN8 |
|---|
| Gene | GPR156 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 814 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (22)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.38
- deafness · score 0.32
- hearing loss, autosomal recessive · score 0.32
- poisoning · score 0.28
- sensorineural hearing loss · score 0.18
- base metabolic rate measurement · score 0.09
- body weight · score 0.06
- lean body mass · score 0.06
- Benign familial chorea · score 0.05
- refractive error measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NFN8-F1 | alphafold | PREDICTED | 55.46 | — |
Amino-acid sequence (814 residues)
MEPEINCSEL CDSFPGQELD RRPLHDLCKT TITSSHHSSK TISSLSPVLL GIVWTFLSCG LLLILFFLAF TIHCRKNRIV KMSSPNLNIV TLLGSCLTYS SAYLFGIQDV LVGSSMETLI QTRLSMLCIG TSLVFGPILG KSWRLYKVFT QRVPDKRVII KDLQLLGLVA ALLMADVILL MTWVLTDPIQ CLQILSVSMT VTGKDVSCTS TSTHFCASRY SDVWIALIWG CKGLLLLYGA YLAGLTGHVS SPPVNQSLTI MVGVNLLVLA AGLLFVVTRY LHSWPNLVFG LTSGGIFVCT TTINCFIFIP QLKQWKAFEE ENQTIRRMAK YFSTPNKSFH TQYGEEENCH PRGEKSSMER LLTEKNAVIE SLQEQVNNAK EKIVRLMSAE CTYDLPEGAA PPASSPNKDV QAVASVHTLA AAQGPSGHLS DFQNDPGMAA RDSQCTSGPS SYAQSLEGPG KDSSFSPGKE EKISDSKDFS DHLDSGCSQK PWTEQSLGPE RGDQVPMNPS QSLLPERGGS DPQRQRHLEN SEEPPERRSR VSSVIREKLQ EVLQDLGLGP EASLSTAPSC HQQTWKNSAA FSPQKMPLSK ELGFSPYMVR RRRAAQRARS HFPGSAPSSV GHRANRTVPG AHSRLHVQNG DSPSLAPQTT DSRVRRPSSR KPSLPSDPQD RPGTLEGSKQ SQTEPEGARG SKAAFLRQPS GSGRAPSPAA PCLSKASPDL PEQWQLWPPV PSGCASLSSQ HSYFDTESSS SDEFFCRCHR PYCEICFQSS SDSSDSGTSD TDPEPTGGLA SWEKLWARSK PIVNFKDDLK PTLV
Explore Probable G-protein coupled receptor 156 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets