Peroxisomal testis-specific protein 1 (PXT1)

About Peroxisomal testis-specific protein 1

Peroxisomal testis-specific protein 1 (PXT1) is a protein from Homo sapiens identified by UniProt accession Q8NFP0, 134 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	Peroxisomal testis-specific protein 1
UniProt accession	Q8NFP0
Gene	PXT1
Organism	Homo sapiens
Length	134 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (23)

Diseases linked to this target (Open Targets).

mean platelet volume · score 0.43
neurodegenerative disease · score 0.36
platelet count · score 0.33
platelet component distribution width · score 0.33
platelet-to-lymphocyte ratio · score 0.23
multiple sclerosis · score 0.20
leukocyte count · score 0.15
Eczematoid dermatitis · score 0.10
allergic rhinitis · score 0.08
mean corpuscular volume · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NFP0-F1	alphafold	PREDICTED	67.15	—

Amino-acid sequence (134 residues)

MKKKHDGIVY ETKEVLNPSP KVTHCCKSLW LKYSFQKAYM TQLVSSQPVP AMSRNPDHNL LSQPKEHSIV QKHHQEEIIH KLAMQLRHIG DNIDHRMVRE DLQQDGRDAL DHFVFFFFRR VQVLLHFFWN NHLL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards