Diphosphoinositol polyphosphate phosphohydrolase 3-alpha (NUDT10)

Homo sapiens — UniProt Q8NFP7

Gene: NUDT10Homo sapiensSwissProt reviewed

About Diphosphoinositol polyphosphate phosphohydrolase 3-alpha

Diphosphoinositol polyphosphate phosphohydrolase 3-alpha (NUDT10) is a protein from Homo sapiens identified by UniProt accession Q8NFP7, 164 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

Target properties

Protein nameDiphosphoinositol polyphosphate phosphohydrolase 3-alpha
UniProt accessionQ8NFP7
GeneNUDT10
OrganismHomo sapiens
Length164 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8NFP7-F1alphafoldPREDICTED88.89—

Amino-acid sequence (164 residues)

MKCKPNQTRT YDPEGFKKRA ACLCFRSERE DEVLLVSSSR YPDRWIVPGG GMEPEEEPGG AAVREVYEEA GVKGKLGRLL GVFEQNQDPK HRTYVYVLTV TELLEDWEDS VSIGRKREWF KVEDAIKVLQ CHKPVHAEYL EKLKLGGSPT NGNSMAPSSP DSDP

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Quick facts

UniProtQ8NFP7
GeneNUDT10
OrganismHomo sapiens
Length164
Binders0
Diseases10
View on UniProt