BPI fold-containing family C protein (BPIFC)

About BPI fold-containing family C protein

BPI fold-containing family C protein (BPIFC) is a protein from Homo sapiens identified by UniProt accession Q8NFQ6, 507 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

Target properties

Protein name	BPI fold-containing family C protein
UniProt accession	Q8NFQ6
Gene	BPIFC
Organism	Homo sapiens
Length	507 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (31)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.28
erythrocyte count · score 0.28
adolescent idiopathic scoliosis · score 0.22
acne · score 0.18
red blood cell density measurement · score 0.17
mean corpuscular volume · score 0.08
insomnia · score 0.06
total blood protein measurement · score 0.06
blood phosphate measurement · score 0.06
Red cell distribution width · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NFQ6-F1	alphafold	PREDICTED	82.91	—

Amino-acid sequence (507 residues)

MCTKTIPVLW GCFLLWNLYV SSSQTIYPGI KARITQRALD YGVQAGMKMI EQMLKEKKLP DLSGSESLEF LKVDYVNYNF SNIKISAFSF PNTSLAFVPG VGIKALTNHG TANISTDWGF ESPLFQDTGG ADLFLSGVYF TGIIILTRND FGHPTLKLQD CYAQLSHAHV SFSGELSVLY NSFAEPMEKP ILKNLNEMLC PIIASEVKAL NANLSTLEVL TKIDNYTLLD YSLISSPEIT ENYLDLNLKG VFYPLENLTD PPFSPVPFVL PERSNSMLYI GIAEYFFKSA SFAHFTAGVF NVTLSTEEIS NHFVQNSQGL GNVLSRIAEI YILSQPFMVR IMATEPPIIN LQPGNFTLDI PASIMMLTQP KNSTVETIVS MDFVASTSVG LVILGQRLVC SLSLNRFRLA LPESNRSNIE VLRFENILSS ILHFGVLPLA NAKLQQGFPL SNPHKFLFVN SDIEVLEGFL LISTDLKYET SSKQQPSFHV WEGLNLISRQ WRGKSAP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards