About Thiosulfate:glutathione sulfurtransferase
Thiosulfate:glutathione sulfurtransferase (TSTD1) is a protein
from Homo sapiens identified by UniProt accession
Q8NFU3, 115 residues long.
MolForge cross-references it against 0 known binders and
84 disease associations.
Target properties
| Protein name | Thiosulfate:glutathione sulfurtransferase |
|---|
| UniProt accession | Q8NFU3 |
|---|
| Gene | TSTD1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 115 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (84)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- monocyte count · score 0.11
- primary familial polycythemia due to EPO receptor mutation · score 0.09
- Blackfan-Diamond anemia · score 0.08
- breast cancer · score 0.07
- monocyte percentage of leukocytes · score 0.07
- erythrocytosis, familial, 3 · score 0.07
- erythrocytosis, familial, 6 · score 0.07
- hemolytic anemia due to diphosphoglycerate mutase deficiency · score 0.07
- lymphocyte count · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NFU3-F1 | alphafold | PREDICTED | 93.68 | — |
Amino-acid sequence (115 residues)
MAGAPTVSLP ELRSLLASGR ARLFDVRSRE EAAAGTIPGA LNIPVSELES ALQMEPAAFQ ALYSAEKPKL EDEHLVFFCQ MGKRGLQATQ LARSLGYTGA RNYAGAYREW LEKES
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