Follicular dendritic cell secreted peptide (FDCSP)

About Follicular dendritic cell secreted peptide

Follicular dendritic cell secreted peptide (FDCSP) is a protein from Homo sapiens identified by UniProt accession Q8NFU4, 85 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

Target properties

Protein name	Follicular dendritic cell secreted peptide
UniProt accession	Q8NFU4
Gene	FDCSP
Organism	Homo sapiens
Length	85 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (41)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.36
breast carcinoma · score 0.05
non-small cell lung carcinoma · score 0.04
COVID-19 · score 0.03
colorectal cancer · score 0.03
psoriasis · score 0.02
chronic rhinosinusitis · score 0.01
cystic fibrosis · score 0.01
ulcerative colitis · score 0.01
chronic interstitial cystitis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NFU4-F1	alphafold	PREDICTED	64.00	—

Amino-acid sequence (85 residues)

MKKVLLLITA ILAVAVGFPV SQDQEREKRS ISDSDELASG FFVFPYPYPF RPLPPIPFPR FPWFRRNFPI PIPESAPTTP LPSEK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards