About Speedy protein E1
Speedy protein E1 (SPDYE1) is a protein
from Homo sapiens identified by UniProt accession
Q8NFV5, 336 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | Speedy protein E1 |
|---|
| UniProt accession | Q8NFV5 |
|---|
| Gene | SPDYE1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 336 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (7)
Diseases linked to this target (Open Targets).
- reticulocyte measurement · score 0.19
- reticulocyte count · score 0.09
- mean platelet volume · score 0.05
- neuronal ceroid lipofuscinosis 1 · score 0.03
- proline measurement · score 0.02
- insomnia · score 0.00
- metopic craniosynostosis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NFV5-F1 | alphafold | PREDICTED | 60.51 | — |
Amino-acid sequence (336 residues)
MQKHYTVAWF LYSAPGVDPS PPCRSLGWKR KREWSDESEE EPEKELAPEP EETWVVETLC GLKMKLKQQR VSPILLEHHK DFNSQLAPGV DPSPPHRSFC WKRKMEWWDK SEESEEEPRK VLAPEPEEIW VAEMLCGLKM KLKRRRVSLV LPEHHEAFNR LLEDPVIKRF LAWDKDLRVS DKYLLAMVIA YFSRAGFPSW QYQRLHFFLA LYLANDMEED DEDSKQNIFH FLYGKNRSRI PLLRKRRFQL YRSMNPRARK NRSHIPLVRK RRFQLRRCMN PRARKNRSQI VLFQKRRFHF FCSMSCRAWV SPEELEEIQA YDPEHWVWAR DRARLS
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