About Syntaxin-binding protein 6
Syntaxin-binding protein 6 (STXBP6) is a protein
from Homo sapiens identified by UniProt accession
Q8NFX7, 210 residues long.
MolForge cross-references it against 0 known binders and
86 disease associations.
Target properties
| Protein name | Syntaxin-binding protein 6 |
|---|
| UniProt accession | Q8NFX7 |
|---|
| Gene | STXBP6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 210 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (86)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.50
- neutrophil count · score 0.49
- leukocyte count · score 0.48
- eosinophil count · score 0.47
- refractive error measurement · score 0.46
- myeloid white cell count · score 0.45
- reticulocyte count · score 0.45
- platelet count · score 0.44
- reticulocyte measurement · score 0.43
- lymphocyte percentage of leukocytes · score 0.43
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NFX7-F1 | alphafold | PREDICTED | 86.56 | — |
Amino-acid sequence (210 residues)
MSAKSAISKE IFAPLDERML GAVQVKRRTK KKIPFLATGG QGEYLTYICL SVTNKKPTQA SITKVKQFEG STSFVRRSQW MLEQLRQVNG IDPNGDSAEF DLLFENAFDQ WVASTASEKC TFFQILHHTC QRYLTDRKPE FINCQSKIMG GNSILHSAAD SVTSAVQKAS QALNERGERL GRAEEKTEDL KNSAQQFAET AHKLAMKHKC
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