Cell adhesion molecule 4 (CADM4)

About Cell adhesion molecule 4

Cell adhesion molecule 4 (CADM4) is a protein from Homo sapiens identified by UniProt accession Q8NFZ8, 388 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.

Target properties

Protein name	Cell adhesion molecule 4
UniProt accession	Q8NFZ8
Gene	CADM4
Organism	Homo sapiens
Length	388 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (66)

Diseases linked to this target (Open Targets).

forced expiratory volume · score 0.16
neutrophil count · score 0.14
leukocyte count · score 0.14
basophil count · score 0.14
blood protein measurement · score 0.13
lymphocyte count · score 0.13
monocyte percentage of leukocytes · score 0.13
lymphocyte percentage of leukocytes · score 0.13
high density lipoprotein cholesterol measurement · score 0.13
neutrophil percentage of leukocytes · score 0.13

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NFZ8-F1	alphafold	PREDICTED	85.27	—

Amino-acid sequence (388 residues)

MGRARRFQWP LLLLWAAAAG PGAGQEVQTE NVTVAEGGVA EITCRLHQYD GSIVVIQNPA RQTLFFNGTR ALKDERFQLE EFSPRRVRIR LSDARLEDEG GYFCQLYTED THHQIATLTV LVAPENPVVE VREQAVEGGE VELSCLVPRS RPAATLRWYR DRKELKGVSS SQENGKVWSV ASTVRFRVDR KDDGGIIICE AQNQALPSGH SKQTQYVLDV QYSPTARIHA SQAVVREGDT LVLTCAVTGN PRPNQIRWNR GNESLPERAE AVGETLTLPG LVSADNGTYT CEASNKHGHA RALYVLVVYD PGAVVEAQTS VPYAIVGGIL ALLVFLIICV LVGMVWCSVR QKGSYLTHEA SGLDEQGEAR EAFLNGSDGH KRKEEFFI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards