Neuropeptide B (NPB)

About Neuropeptide B

Neuropeptide B (NPB) is a protein from Homo sapiens identified by UniProt accession Q8NG41, 125 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

Target properties

Protein name	Neuropeptide B
UniProt accession	Q8NG41
Gene	NPB
Organism	Homo sapiens
Length	125 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (31)

Diseases linked to this target (Open Targets).

MODY · score 0.06
Obesity · score 0.05
obesity · score 0.05
Sertoli Cell-Only Syndrome · score 0.04
metabolic syndrome X · score 0.04
type 1 diabetes mellitus · score 0.02
infection · score 0.02
infect · score 0.02
anorexia nervosa · score 0.02
viral disease · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NG41-F1	alphafold	PREDICTED	69.37	—

Amino-acid sequence (125 residues)

MARSATLAAA ALALCLLLAP PGLAWYKPAA GHSSYSVGRA AGLLSGLRRS PYARRSQPYR GAEPPGGAGA SPELQLHPRL RSLAVCVQDV APNLQRCERL PDGRGTYQCK ANVFLSLRAA DCLAA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards