About Olfactory receptor 5T1
Olfactory receptor 5T1 (OR5T1) is a protein
from Homo sapiens identified by UniProt accession
Q8NG75, 326 residues long.
MolForge cross-references it against 0 known binders and
11 disease associations.
Target properties
| Protein name | Olfactory receptor 5T1 |
| UniProt accession | Q8NG75 |
| Gene | OR5T1 |
| Organism | Homo sapiens |
| Length | 326 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.21
- clear cell renal carcinoma · score 0.18
- ovarian cancer · score 0.18
- prostate adenocarcinoma · score 0.18
- pancreatic adenocarcinoma · score 0.18
- hepatocellular carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- diffuse large B-cell lymphoma · score 0.10
- age at menarche · score 0.03
- leukocyte count · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q8NG75-F1 | alphafold | PREDICTED | 87.17 | — |
Amino-acid sequence (326 residues)
MSGLPSDMDL YKLQLNNFTE VTMFILISFT EEFDVQVFLF LLFLAIYLFT LIGNLGLVVP IIGDFWLHSP MYYFLGVLSF LDVCYSTVVT PKMLVNFLAK NKSISFLGCA TQMFLACTFG TTECFLLAAM AYDRYVAIYN PLLYSVSMSP RVYVPLITAS YVASILHATI HTVATFSLSF CGSNEIRHVF CNMPPLLAIS CSDTHVIQLL FFYFVGSIEI VTILIVLISY GFILLAILKM QSAEGRRKVF STCGAHLTGV TIYHGTILFM YVRPSSSYTS DNDMIVSIFY TIVIPMLNPI IYSLRNKDVK EAIKRLLVRN WFINKL
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