Olfactory receptor 2T33 (OR2T33)

About Olfactory receptor 2T33

Olfactory receptor 2T33 (OR2T33) is a protein from Homo sapiens identified by UniProt accession Q8NG76, 320 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein name	Olfactory receptor 2T33
UniProt accession	Q8NG76
Gene	OR2T33
Organism	Homo sapiens
Length	320 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (13)

Diseases linked to this target (Open Targets).

thyroid gland adenocarcinoma · score 0.22
ovarian cancer · score 0.18
prostate adenocarcinoma · score 0.18
low grade glioma · score 0.18
breast adenocarcinoma · score 0.18
brain measurement · score 0.16
white matter microstructure measurement · score 0.11
brain volume measurement · score 0.10
reticulocyte measurement · score 0.04
adolescent idiopathic scoliosis · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NG76-F1	alphafold	PREDICTED	88.72	—

Amino-acid sequence (320 residues)

MEMRNTTPDF ILLGLFNHTR AHQVLFMMVL SIVLTSLFGN SLMILLIHWD HRLHTPMYFL LSQLSLMDMM LVSTTVPKMA ADYLTGSKAI SRAGCGVQIF FLPTLGGGEC FLLAAMAYDR YAAVCHPLRY PTLMSWQLCL RMTMSCWLLG AADGLLQAVV TLSFPYCGAH EIDHFFCETP VLVRLACADT SVFENAMYIC CVLMLLVPFS LILSSYGLIL AAVLHMRSTE ARKKAFATCS SHVAVVGLFY GAAIFTYMRP KSHRSTNHDK VVSAFYTMFT PLLNPLIYSV KNSEVKGALK RWLGTCVNIK HQQNEAHRSR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards