About Olfactory receptor 2T12
Olfactory receptor 2T12 (OR2T12) is a protein
from Homo sapiens identified by UniProt accession
Q8NG77, 320 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Olfactory receptor 2T12 |
|---|
| UniProt accession | Q8NG77 |
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| Gene | OR2T12 |
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| Organism | Homo sapiens |
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| Length | 320 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.18
- hepatocellular carcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- adolescent idiopathic scoliosis · score 0.11
- sensory perception of smell · score 0.09
- reticulocyte measurement · score 0.03
- gastric carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NG77-F1 | alphafold | PREDICTED | 88.89 | — |
Amino-acid sequence (320 residues)
MEMRNTTPDF ILLGLFNHTR AHQVLFMMLL ATVLTSLFSN ALMILLIHWD HRLHRPMYFL LSQLSLMDMM LVSTTVPKMA ADYLTGNKAI SRAGCGVQIF FLPTLGGGEC FLLAAMAYDR YAAVCHPLRY PTLMSWQLCL RMTMSSWLLG AADGLLQAVA TLSFPYCGAH EIDHFFCEAP VLVRLACADT SVFENAMYIC CVLMLLVPFS LILSSYGLIL AAVLLMRSTE ARKKAFATCS SHVAVVGLFY GAGIFTYMRP KSHRSTNHDK VVSAFYTMFT PLLNPLIYSV RNSEVKEALK RWLGTCVNLK HQQNEAHRSR
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