About Olfactory receptor 2L5
Olfactory receptor 2L5 (OR2L5) is a protein
from Homo sapiens identified by UniProt accession
Q8NG80, 312 residues long.
MolForge cross-references it against 0 known binders and
6 disease associations.
Target properties
| Protein name | Olfactory receptor 2L5 |
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| UniProt accession | Q8NG80 |
|---|
| Gene | OR2L5 |
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| Organism | Homo sapiens |
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| Length | 312 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (6)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- signet ring cell carcinoma · score 0.01
- chronic myelogenous leukemia · score 0.01
- small cell lung carcinoma · score 0.00
- acute myeloid leukemia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NG80-F1 | alphafold | PREDICTED | 90.72 | — |
Amino-acid sequence (312 residues)
MENYNQTSTD FILLGLFPPS KIGLFLFILF VLIFLMALIG NLSMILLIFL DTHLHTPMYF LLSQLSLIDL NYISTIVPKM ASDFLYGNKS ISFIGCGIQS FFFMTFAGAE ALLLTSMAYD RYVAICFPLH YPIRMSKRMY VLMITGSWMI GSINSCAHTV YAFRIPYCKS RAINHFFCDV PAMLTLACTD TWVYEYTVFL SSTIFLVFPF TGIACSYGWV LLAVYRMHSA EGRKKAYSTC STHLTVVTFY YAPFAYTYLC PRSLRSLTED KVLAVFYTIL TPMLNPIIYS LRNKEVMGAL TRVIQNIFSV KM
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