About Olfactory receptor 2M3
Olfactory receptor 2M3 (OR2M3) is a protein
from Homo sapiens identified by UniProt accession
Q8NG83, 312 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | Olfactory receptor 2M3 |
|---|
| UniProt accession | Q8NG83 |
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| Gene | OR2M3 |
|---|
| Organism | Homo sapiens |
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| Length | 312 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (13)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.28
- thyroid gland adenocarcinoma · score 0.22
- prostate adenocarcinoma · score 0.18
- low grade glioma · score 0.18
- ovarian cancer · score 0.18
- acute myeloid leukemia · score 0.14
- functional brain measurement · score 0.12
- brain measurement · score 0.12
- diffuse large B-cell lymphoma · score 0.10
- breast carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NG83-F1 | alphafold | PREDICTED | 85.06 | — |
Amino-acid sequence (312 residues)
MARENSTFNS DFILLGIFNH SPTHTFLFFL VLAIFSVAFM GNSVMVLLIY LDTQLHTPMY LLLSQLSLMD LMLICTTVPK MAFNYLSGSK SISMAGCATQ IFFYTSLLGS ECFLLAVMAY DRYTAICHPL RYTNLMSPKI CGLMTAFSWI LGSTDGIIDV VATFSFSYCG SREIAHFFCD FPSLLILSCS DTSIFEKILF ICCIVMIVFP VAIIIASYAR VILAVIHMGS GEGRRKAFTT CSSHLLVVGM YYGAALFMYI RPTSDRSPTQ DKMVSVFYTI LTPMLNPLIY SLRNKEVTRA FMKILGKGKS GE
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