About Olfactory receptor 1M1
Olfactory receptor 1M1 (OR1M1) is a protein
from Homo sapiens identified by UniProt accession
Q8NGA1, 313 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | Olfactory receptor 1M1 |
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| UniProt accession | Q8NGA1 |
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| Gene | OR1M1 |
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| Organism | Homo sapiens |
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| Length | 313 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (13)
Diseases linked to this target (Open Targets).
- low grade glioma · score 0.18
- clear cell renal carcinoma · score 0.18
- prostate adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- asthma · score 0.06
- cancer antigen 125 measurement · score 0.05
- respiratory system disease · score 0.04
- colorectal adenocarcinoma · score 0.04
- neuroblastoma · score 0.03
- suicide behaviour measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGA1-F1 | alphafold | PREDICTED | 89.16 | — |
Amino-acid sequence (313 residues)
MEPRNQTSAS QFILLGLSEK PEQETLLFSL FFCMYLVMVV GNLLIILAIS IDSHLHTPMY FFLANLSLVD FCLATNTIPK MLVSLQTGSK AISYPCCLIQ MYFFHFFGIV DSVIIAMMAY DRFVAICHPL HYAKIMSLRL CRLLVGALWA FSCFISLTHI LLMARLVFCG SHEVPHYFCD LTPILRLSCT DTSVNRIFIL IVAGMVIATP FVCILASYAR ILVAIMKVPS AGGRKKAFST CSSHLSVVAL FYGTTIGVYL CPSSVLTTVK EKASAVMYTA VTPMLNPFIY SLRNRDLKGA LRKLVNRKIT SSS
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