About Olfactory receptor 10H4
Olfactory receptor 10H4 (OR10H4) is a protein
from Homo sapiens identified by UniProt accession
Q8NGA5, 316 residues long.
MolForge cross-references it against 0 known binders and
10 disease associations.
Target properties
| Protein name | Olfactory receptor 10H4 |
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| UniProt accession | Q8NGA5 |
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| Gene | OR10H4 |
|---|
| Organism | Homo sapiens |
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| Length | 316 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (10)
Diseases linked to this target (Open Targets).
- chronic lymphocytic leukemia · score 0.18
- pancreatic adenocarcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- aspartate aminotransferase measurement · score 0.05
- age at onset · score 0.04
- Myopia · score 0.04
- heel bone mineral density · score 0.03
- glioblastoma multiforme · score 0.01
- gastric carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGA5-F1 | alphafold | PREDICTED | 86.89 | — |
Amino-acid sequence (316 residues)
MPSQNYSIIS EFNLFGFSAF PQHLLPILFL LYLLMFLFTL LGNLLIMATI WIEHRLHTPM YLFLCTLSVS EILFTVAITP RMLADLLSTH HSITFVACAN QMFFSFMFGF THSFLLLVMG YDRYVAICHP LRYNVLMSPR DCAHLVACTW AGGSVMGMMV TTIVFHLTFC GSNVIHHFFC HVLSLLKLAC ENKTSSVIMG VMLVCVTALI GCLFLIILSY VFIVAAILRI PSAEGRHKTF STCVSHLTVV VTHYSFASFI YLKPKGLHSM YSDALMATTY TVFTPFLSPI IFSLRNKELK NAINKNFYRK FCPPSS
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