About Olfactory receptor 10H5
Olfactory receptor 10H5 (OR10H5) is a protein
from Homo sapiens identified by UniProt accession
Q8NGA6, 315 residues long.
MolForge cross-references it against 0 known binders and
11 disease associations.
Target properties
| Protein name | Olfactory receptor 10H5 |
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| UniProt accession | Q8NGA6 |
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| Gene | OR10H5 |
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| Organism | Homo sapiens |
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| Length | 315 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (11)
Diseases linked to this target (Open Targets).
- chronic lymphocytic leukemia · score 0.18
- clear cell renal carcinoma · score 0.18
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- breast adenocarcinoma · score 0.18
- breast carcinoma · score 0.03
- age at onset · score 0.02
- Myopia · score 0.02
- gastric carcinoma · score 0.01
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGA6-F1 | alphafold | PREDICTED | 88.13 | — |
Amino-acid sequence (315 residues)
MQGLNHTSVS EFILVGFSAF PHLQLMLFLL FLLMYLFTLL GNLLIMATVW SERSLHMPMY LFLCALSITE ILYTVAIIPR MLADLLSTQR SIAFLACASQ MFFSFSFGFT HSFLLTVMGY DRYVAICHPL RYNVLMSLRG CTCRVGCSWA GGLVMGMVVT SAIFHLAFCG HKEIHHFFCH VPPLLKLACG DDVLVVAKGV GLVCITALLG CFLLILLSYA FIVAAILKIP SAEGRNKAFS TCASHLTVVV VHYGFASVIY LKPKGPQSPE GDTLMGITYT VLTPFLSPII FSLRNKELKV AMKKTCFTKL FPQNC
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