About Olfactory receptor 10G2
Olfactory receptor 10G2 (OR10G2) is a protein
from Homo sapiens identified by UniProt accession
Q8NGC3, 310 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Olfactory receptor 10G2 |
|---|
| UniProt accession | Q8NGC3 |
|---|
| Gene | OR10G2 |
|---|
| Organism | Homo sapiens |
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| Length | 310 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- clear cell renal carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- monocyte count · score 0.09
- Myopia · score 0.08
- age at onset · score 0.08
- sleep measurement · score 0.02
- childhood leukemia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGC3-F1 | alphafold | PREDICTED | 87.35 | — |
Amino-acid sequence (310 residues)
MGKTKNTSLD AVVTDFILLG LSHPPNLRSL LFLVFFIIYI LTQLGNLLIL LTMWADPKLC ARPMYILLGV LSFLDMWLSS VTVPLLILDF TPSIKAIPFG GCVAQLYFFH FLGSTQCFLY TLMAYDRYLA ICQPLRYPVL MNGRLCTVLV AGAWVAGSMH GSIQATLTFR LPYCGPNQVD YFICDIPAVL RLACADTTVN ELVTFVDVGV VAASCFMLIL LSYANIVNAI LKIRTTDGRR RAFSTCGSHL IVVTVYYVPC IFIYLRAGSK DPLDGAAAVF YTVVTPLLNP LIYTLRNQEV KSALKRITAG
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