About Olfactory receptor 10G3
Olfactory receptor 10G3 (OR10G3) is a protein
from Homo sapiens identified by UniProt accession
Q8NGC4, 313 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Olfactory receptor 10G3 |
|---|
| UniProt accession | Q8NGC4 |
|---|
| Gene | OR10G3 |
|---|
| Organism | Homo sapiens |
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| Length | 313 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- diet measurement · score 0.40
- neurodegenerative disease · score 0.24
- clear cell renal carcinoma · score 0.18
- multiple myeloma · score 0.16
- Myopia · score 0.05
- age at onset · score 0.05
- gastric carcinoma · score 0.00
- diabetes mellitus · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGC4-F1 | alphafold | PREDICTED | 87.70 | — |
Amino-acid sequence (313 residues)
MERINSTLLT AFILTGIPYP LRLRTLFFVF FFLIYILTQL GNLLILITVW ADPRLHARPM YIFLGVLSVI DMSISSIIVP RLMMNFTLGV KPIPFGGCVA QLYFYHFLGS TQCFLYTLMA YDRYLAICQP LRYPVLMTAK LSALLVAGAW MAGSIHGALQ AILTFRLPYC GPNQVDYFFC DIPAVLRLAC ADTTVNELVT FVDIGVVVAS CFSLILLSYI QIIQAILRIH TADGRRRAFS TCGAHVTVVT VYYVPCAFIY LRPETNSPLD GAAALVPTAI TPFLNPLIYT LRNQEVKLAL KRMLRSPRTP SEV
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