Olfactory receptor 4K17 (OR4K17)

About Olfactory receptor 4K17

Olfactory receptor 4K17 (OR4K17) is a protein from Homo sapiens identified by UniProt accession Q8NGC6, 312 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	Olfactory receptor 4K17
UniProt accession	Q8NGC6
Gene	OR4K17
Organism	Homo sapiens
Length	312 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

neuroblastoma · score 0.21
low grade glioma · score 0.18
breast adenocarcinoma · score 0.18
monocyte count · score 0.02
total blood protein measurement · score 0.02
insomnia · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGC6-F1	alphafold	PREDICTED	86.65	—

Amino-acid sequence (312 residues)

MKLLNQSQVS EFILLGLTSS QDVEFLLFAL FSVIYVVTVL GNLLIIVTVF NTPNLNTPMY FLLGNLSFVD MTLASFATPK VILNLLKKQK VISFAGCFTQ IFLLHLLGGV EMVLLVSMAF DRYVAICKPL HYMTIMNKKV CVLLVVTSWL LGLLHSGFQI PFAVNLPFCG PNVVDSIFCD LPLVTKLACI DIYFVQVVIV ANSGIISLSC FIILLISYSL ILITIKNHSP TGQSKARSTL TAHITVVILF FGPCIFIYIW PFGNHSVDKF LAVFYTIITP ILNPIIYTLR NKEMKISMKK LWRAFVNSRE DT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards