Olfactory receptor 4M1 (OR4M1)

About Olfactory receptor 4M1

Olfactory receptor 4M1 (OR4M1) is a protein from Homo sapiens identified by UniProt accession Q8NGD0, 313 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein name	Olfactory receptor 4M1
UniProt accession	Q8NGD0
Gene	OR4M1
Organism	Homo sapiens
Length	313 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (49)

Diseases linked to this target (Open Targets).

thyroid gland adenocarcinoma · score 0.22
neuroblastoma · score 0.21
clear cell renal carcinoma · score 0.18
low grade glioma · score 0.18
breast adenocarcinoma · score 0.18
obesity due to melanocortin 4 receptor deficiency · score 0.05
CIDEC-related familial partial lipodystrophy · score 0.05
obesity due to prohormone convertase I deficiency · score 0.05
PPARG-related familial partial lipodystrophy · score 0.04
AKT2-related familial partial lipodystrophy · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGD0-F1	alphafold	PREDICTED	89.70	—

Amino-acid sequence (313 residues)

METANYTKVT EFVLTGLSQT REVQLVLFVI FLSFYLFILP GNILIICTIR LDPHLTSPMY FLLANLALLD IWYSSITAPK MLIDFFVERK IISFGGCIAQ LFFLHFVGAS EMFLLTVMAY DRYAAICRPL HYATIMNRRL CCILVALSWM GGFIHSIIQV ALIVRLPFCG PNELDSYFCD ITQVVRIACA NTFPEELVMI CSSGLISVVC FIALLMSYAF LLALLKKHSG SGENTNRAMS TCYSHITIVV LMFGPSIYIY ARPFDSFSLD KVVSVFHTVI FPLLNPIIYT LRNKEVKAAM RKVVTKYILC EEK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards