About Olfactory receptor 4N2
Olfactory receptor 4N2 (OR4N2) is a protein
from Homo sapiens identified by UniProt accession
Q8NGD1, 307 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | Olfactory receptor 4N2 |
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| UniProt accession | Q8NGD1 |
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| Gene | OR4N2 |
|---|
| Organism | Homo sapiens |
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| Length | 307 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (7)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- clear cell renal carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- blood protein measurement · score 0.05
- central nervous system cancer · score 0.01
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGD1-F1 | alphafold | PREDICTED | 87.52 | — |
Amino-acid sequence (307 residues)
MESENRTVIR EFILLGLTQS QDIQLLVFVL VLIFYFIILP GNFLIIFTIK SDPGLTAPLY FFLGNLAFLD ASYSFIVAPR MLVDFLSAKK IISYRGCITQ LFFLHFLGGG EGLLLVVMAF DRYIAICRPL HYPTVMNPRT CYAMMLALWL GGFVHSIIQV VLILRLPFCG PNQLDNFFCD VPQVIKLACT DTFVVELLMV FNSGLMTLLC FLGLLASYAV ILCRIRGSSS EAKNKAMSTC ITHIIVIFFM FGPGIFIYTR PFRAFPADKV VSLFHTVIFP LLNPVIYTLR NQEVKASMKK VFNKHIA
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