About Olfactory receptor 4K2
Olfactory receptor 4K2 (OR4K2) is a protein
from Homo sapiens identified by UniProt accession
Q8NGD2, 314 residues long.
MolForge cross-references it against 0 known binders and
10 disease associations.
Target properties
| Protein name | Olfactory receptor 4K2 |
|---|
| UniProt accession | Q8NGD2 |
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| Gene | OR4K2 |
|---|
| Organism | Homo sapiens |
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| Length | 314 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (10)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- clear cell renal carcinoma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- pancreatic adenocarcinoma · score 0.04
- breast carcinoma · score 0.04
- blood protein measurement · score 0.03
- gastric carcinoma · score 0.01
- malignant pleural mesothelioma · score 0.00
- central nervous system cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGD2-F1 | alphafold | PREDICTED | 86.06 | — |
Amino-acid sequence (314 residues)
MDVGNKSTMS EFVLLGLSNS WELQMFFFMV FSLLYVATMV GNSLIVITVI VDPHLHSPMY FLLTNLSIID MSLASFATPK MITDYLTGHK TISFDGCLTQ IFFLHLFTGT EIILLMAMSF DRYIAICKPL HYASVISPQV CVALVVASWI MGVMHSMSQV IFALTLPFCG PYEVDSFFCD LPVVFQLACV DTYVLGLFMI STSGIIALSC FIVLFNSYVI VLVTVKHHSS RGSSKALSTC TAHFIVVFLF FGPCIFIYMW PLSSFLTDKI LSVFYTIFTP TLNPIIYTLR NQEVKIAMRK LKNRFLNFNK AMPS
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