About Olfactory receptor 4K5
Olfactory receptor 4K5 (OR4K5) is a protein
from Homo sapiens identified by UniProt accession
Q8NGD3, 323 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | Olfactory receptor 4K5 |
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| UniProt accession | Q8NGD3 |
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| Gene | OR4K5 |
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| Organism | Homo sapiens |
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| Length | 323 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (7)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- neuroblastoma · score 0.21
- clear cell renal carcinoma · score 0.18
- gastric carcinoma · score 0.01
- AIDS dementia · score 0.00
- diabetes mellitus · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGD3-F1 | alphafold | PREDICTED | 85.50 | — |
Amino-acid sequence (323 residues)
MDKSNSSVVS EFVLLGLCSS QKLQLFYFCF FSVLYTVIVL GNLLIILTVT SDTSLHSPMY FLLGNLSFVD ICQASFATPK MIADFLSAHE TISFSGCIAQ IFFIHLFTGG EMVLLVSMAY DRYVAICKPL YYVVIMSRRT CTVLVMISWA VSLVHTLSQL SFTVNLPFCG PNVVDSFFCD LPRVTKLACL DSYIIEILIV VNSGILSLST FSLLVSSYII ILVTVWLKSS AAMAKAFSTL ASHIAVVILF FGPCIFIYVW PFTISPLDKF LAIFYTVFTP VLNPIIYTLR NRDMKAAVRK IVNHYLRPRR ISEMSLVVRT SFH
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