About Olfactory receptor 4K1
Olfactory receptor 4K1 (OR4K1) is a protein
from Homo sapiens identified by UniProt accession
Q8NGD4, 311 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | Olfactory receptor 4K1 |
|---|
| UniProt accession | Q8NGD4 |
|---|
| Gene | OR4K1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 311 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (7)
Diseases linked to this target (Open Targets).
- pancreatic adenocarcinoma · score 0.18
- hepatocellular carcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
- chronic lymphocytic leukemia · score 0.18
- ovarian cancer · score 0.18
- multiple myeloma · score 0.16
- AIDS dementia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGD4-F1 | alphafold | PREDICTED | 83.94 | — |
Amino-acid sequence (311 residues)
MAHTNESMVS EFVLLGLSNS WGLQLFFFAI FSIVYVTSVL GNVLIIVIIS FDSHLNSPMY FLLSNLSFID ICQSNFATPK MLVDFFIERK TISFEGCMAQ IFVLHSFVGS EMMLLVAMAY DRFIAICKPL HYSTIMNRRL CVIFVSISWA VGVLHSVSHL AFTVDLPFCG PNEVDSFFCD LPLVIELACM DTYEMEIMTL TNSGLISLSC FLALIISYTI ILIGVRCRSS SGSSKALSTL TAHITVVILF FGPCIYFYIW PFSRLPVDKF LSVFYTVCTP LLNPIIYSLR NEDVKAAMWK LRNRHVNSWK N
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