Olfactory receptor 2AP1 (OR2AP1)

About Olfactory receptor 2AP1

Olfactory receptor 2AP1 (OR2AP1) is a protein from Homo sapiens identified by UniProt accession Q8NGE2, 309 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	Olfactory receptor 2AP1
UniProt accession	Q8NGE2
Gene	OR2AP1
Organism	Homo sapiens
Length	309 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

hepatocellular carcinoma · score 0.18
heart rate · score 0.03
response to beta blocker · score 0.03
neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGE2-F1	alphafold	PREDICTED	89.26	—

Amino-acid sequence (309 residues)

MKNKTVLTEF ILLGLTDVPE LQVAVFTFLF LAYLLSILGN LTILILTLLD SHLQTPMYFF LRNFSFLEIS FTNIFIPRVL ISITTGNKSI SFAGCFTQYF FAMFLGATEF YLLAAMSYDR YVAICKPLHY TTIMSSRICI QLIFCSWLGG LMAIIPTITL MSQQDFCASN RLNHYFCDYE PLLELSCSDT SLIEKVVFLV ASVTLVVTLV LVILSYAFII KTILKLPSAQ QRTKAFSTCS SHMIVISLSY GSCMFMYINP SAKEGDTFNK GVALLITSVA PLLNPFIYTL RNQQVKQPFK DMVKKLLNL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards