About Olfactory receptor 4B1
Olfactory receptor 4B1 (OR4B1) is a protein
from Homo sapiens identified by UniProt accession
Q8NGF8, 309 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Olfactory receptor 4B1 |
|---|
| UniProt accession | Q8NGF8 |
|---|
| Gene | OR4B1 |
|---|
| Organism | Homo sapiens |
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| Length | 309 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (30)
Diseases linked to this target (Open Targets).
- clear cell renal carcinoma · score 0.18
- pancreatic adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- insulin like growth factor measurement · score 0.14
- acute myeloid leukemia · score 0.14
- mean platelet volume · score 0.14
- sleep duration · score 0.14
- glomerular filtration rate · score 0.08
- lymphocyte count · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGF8-F1 | alphafold | PREDICTED | 87.04 | — |
Amino-acid sequence (309 residues)
MASTSNVTEL IFTGLFQDPA VQSVCFVVFL PVYLATVVGN GLIVLTVSIS KSLDSPMYFF LSCLSLVEIS YSSTIAPKFI IDLLAKIKTI SLEGCLTQIF FFHFFGVAEI LLIVVMAYDC YVAICKPLHY MNIISRQLCH LLVAGSWLGG FCHSIIQILV IIQLPFCGPN VIDHYFCDLQ PLFKLACTDT FMEGVIVLAN SGLFSVFSFL ILVSSYIVIL VNLRNHSAEG RHKALSTCAS HITVVILFFG PAIFLYMRPS STFTEDKLVA VFYTVITPML NPIIYTLRNA EVKIAIRRLW SKKENPGRE
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